← The FormularyDrive & vitalityTribulus
Also known as Tribulus terrestris / puncture vineThe most famous claim in the aisle. The evidence says otherwise.
Tribulus is the ingredient most responsible for the phrase 'test booster', and the honest reading of the literature is that it does not do that. A 2025 systematic review of controlled trials in men found no significant change in androgen levels in eight of ten studies, with the two exceptions in men who were hypogonadal to begin with. So why is it here? Because there is a separate, older story — centuries of traditional use for libido and vitality — and that is the claim we make and the only one we can. If a label promises you testosterone from tribulus, the label has not read the papers.
A low-growing Mediterranean and Asian vine, used in Ayurvedic and Chinese practice long before the supplement industry found it.
The studied compounds are steroidal saponins, chiefly protodioscin. The popular theory is that these raise luteinising hormone and therefore testosterone. The theory is clean; the human data do not cooperate, which is the most interesting thing about this plant.
Traditionally used to support libido and vitality. It is in PRIME's botanical blend for that traditional role, not for a hormonal one.
Men who want the traditional botanical for what it is. Anyone chasing an actual hormone problem should be getting a blood test, not a capsule.
Daily inside PRIME's blend, with food. Judged over weeks as part of the whole formula.
Nothing measurable in a blood test, on the current evidence. Whatever traditional use describes is subjective and slow.
Grade C. A 2025 systematic review of clinical trials on erectile function and testosterone found no robust evidence for raising testosterone; the trials reporting an increase were in hypogonadal men. Safety at supplement doses appears reasonable, but the ingredient's fame vastly exceeds its file.
Read the labelNot a testosterone treatment and not an erection product — the evidence does not support either. Speak to a doctor first if you take diabetes or blood-pressure medication, or have a hormone-sensitive condition.
Evidence grades describe how well an ingredient is studied — A well-supported, C emerging — not a promise of results. Educational, not medical advice. Doses are typical ranges; follow the label on the product.