Silvery-green artichoke leaves with a purple-tinged choke fragment. ← The FormularyDigestion

Artichoke leaf

Also known as Cynara scolymus
CEVIDENCE

Traditional bitter. The claims were assessed and turned down.

The honest take
Artichoke is one of those ingredients with centuries of use, a plausible mechanism and a disappointing evidence file. Regulators looked at the digestive claims and said no. It is here at a real dose of 500 mg as the botanical half of a bile formula, and it is fair to call it traditional. It is not fair to call it proven, and plenty of labels do.
What it is
An extract of the artichoke leaf, not the part you eat, used as a digestive bitter across southern Europe for a very long time.
How it works
Cynarin and related compounds are thought to stimulate bile flow, which is the mechanism behind its use with fatty meals. Plausible, and not established in humans to a standard that carries a claim.
What it does
Traditionally taken before or with rich food. The trials have not produced anything an authority would let us claim.
Who it's for
Anyone taking it as part of a digestive formula rather than expecting it to do the work alone.
How to use it
500 mg with a meal.
What to expect
Subtle. This is not an ingredient you feel.
The research
Grade C. Health claims assessed and rejected. Safety is good outside of gallstones, bile duct obstruction and asteraceae allergy.

Read the labelDo not use with a bile duct obstruction, and ask a doctor first if you have gallstones — this stimulates bile flow, which is exactly what a stone does not need. Related to daisies and ragweed, so relevant to those allergies.

Evidence grades describe how well an ingredient is studied — A well-supported, C emerging — not a promise of results. Educational, not medical advice. Doses are typical ranges; follow the label on the product.